GLS- Plus Soft Geletin Capsule Now Available in Bangladesh

GLS PLUS LITERATURE INGRIDENT 

1. OMEGA 3 FATY ACID 

2. EPA

3. DHA 

4. L-GLUTATHIONE 

5. GINSENG EXTRACT 

6. GINKGO BIOA EXTRACT

7. GREEN TEA EXTRACT 

8. GRAPE SEED EXTRACT 

9. NATURAL MIXED CARTENOIDS 

10. CITRUS BIOAVONOIDS 

11. WHEAT GERM OIL 

12. BIOTIN 

13. VIKATIM K,B3,B6,B12,D3 

14.  IRON, CALCIUM, MAGANESE, POTASIUM, COPPER, PHOSPHORUS, ZINC, CHROMIUM, MOLBEDENUM, LACTIC ACID OMEGA 3 FATTY ACID WHAT IS OMEGA 3 FATTY ACID :- Omega−3 fatty acids, also called Omega-3 oils, ω−3 fatty acids or n−3 fatty acids,[1] are polyunsaturated fatty acids (PUFAs) characterized by the presence of a double bond, three atoms away from the terminal methyl group in their chemical structure.[2] They are widely distributed in nature, being important constituents of animal lipid metabolism, and they play an important role in the human diet and in human physiology.[3][4] The three types of omega−3 fatty acids involved in human physiology are α-linolenic acid (ALA), eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA). ALA can be found in plants, while DHA and EPA are found in algae and fish. Marine algae and phytoplankton are primary sources of omega−3 fatty acids.[5] DHA and EPA accumulate in fish that eat these algae.[6] Common sources of plant oils containing ALA include walnuts, edible seeds, and flaxseeds, while sources of EPA and DHA include fish and fish oils,[1] as well as algae oil. Mammals are unable to synthesize the essential omega−3 fatty acid ALA and can only obtain it through diet. However, they can use ALA, when available, to form EPA and DHA, by creating additional double bonds along its carbon chain (desaturation) and extending it (elongation). Namely, ALA (18 carbons and 3 double bonds) is used to make EPA (20 carbons and 5 double bonds), which is then used to make DHA (22 carbons and 6 double bonds).[1][2] The ability to make the longer-chain omega−3 fatty acids from ALA may be impaired in aging.[7] In foods exposed to air, unsaturated fatty acids are vulnerable to oxidation and rancidity.[2][8] Health effects The association between supplementation and a lower risk of all-cause mortality appears inconclusive.[22][12] Cancer The evidence linking the consumption of marine omega−3 fats to a lower risk of cancer is poor.[1][23] With the possible exception of breast cancer,[1][24][25] there is insufficient evidence that supplementation with omega−3 fatty acids has an effect on different cancers.[26][27] The effect of consumption on prostate cancer is not conclusive.[1][25] There is a decreased risk with higher blood levels of DPA, but possibly an increased risk of more aggressive prostate cancer was shown with higher blood levels of combined EPA and DHA.[28] In people with advanced cancer and cachexia, omega−3 fatty acids supplements may be of benefit, improving appetite, weight, and quality of life.[29] Cardiovascular disease Moderate and high quality evidence from a 2020 review showed that EPA and DHA, such as that found in omega−3 polyunsaturated fatty acid supplements, does not appear to improve mortality or cardiovascular health.[9] There is weak evidence indicating that α-linolenic acid may be associated with a small reduction in the risk of a cardiovascular event or the risk of arrhythmia.[2][9] A 2018 meta-analysis found no support that daily intake of one gram of omega−3 fatty acid in individuals with a history of coronary heart disease prevents fatal coronary heart disease, nonfatal myocardial infarction or any other vascular event.[12] However, omega−3 fatty acid supplementation greater than one gram daily for at least a year may be protective against cardiac death, sudden death, and myocardial infarction in people who have a history of cardiovascular disease.[30] No protective effect against the development of stroke or all-cause mortality was seen in this population.[30] A 2018 study found that omega−3 supplementation was helpful in protecting cardiac health in those who did not regularly eat fish, particularly in the African American population.[31] Eating a diet high in fish that contain long chain omega−3 fatty acids does appear to decrease the risk of stroke.[32] Fish oil supplementation has not been shown to benefit revascularization or abnormal heart rhythms and has no effect on heart failure hospital admission rates.[33] Furthermore, fish oil supplement studies have failed to support claims of preventing heart attacks or strokes.[13] In the EU, a review by the European Medicines Agency of omega−3 fatty acid medicines containing a combination of an ethyl ester of eicosapentaenoic acid and docosahexaenoic acid at a dose of 1 g per day concluded that these medicines are not effective in secondary prevention of heart problems in patients who have had a myocardial infarction.[34] Evidence suggests that omega−3 fatty acids modestly lower blood pressure (systolic and diastolic) in people with hypertension and in people with normal blood pressure.[35][36] Omega−3 fatty acids can also reduce heart rate,[37] an emerging risk factor. Some evidence suggests that people with certain circulatory problems, such as varicose veins, may benefit from the consumption of EPA and DHA, which may stimulate blood circulation and increase the breakdown of fibrin, a protein involved in blood clotting and scar formation. Omega−3 fatty acids reduce blood triglyceride levels, but do not significantly change the level of LDL cholesterol or HDL cholesterol.[38][39] The American Heart Association position (2011) is that borderline elevated triglycerides, defined as 150–199 mg/dL, can be lowered by 0.5–1.0 grams of EPA and DHA per day; high triglycerides 200–499 mg/dL benefit from 1–2 g/day; and >500 mg/dL be treated under a physician's supervision with 2–4 g/day using a prescription product.[40] In this population omega−3 fatty acid supplementation decreases the risk of heart disease by about 25%.[41] A 2019 review found that omega-3 fatty acid supplements make little or no difference to cardiovascular mortality and that patients with myocardial infarction yield no benefit in taking the supplements.[42] A 2021 review found that omega-3 supplementation did not affect cardiovascular disease outcomes.[11] A 2021 meta-analysis showed that use of marine omega-3 supplementation was associated with an increased risk of atrial fibrillation, with the risk appearing to increase for doses greater than one gram per day.[43] Biochemistry Transporters DHA in the form of lysophosphatidylcholine is transported into the brain by a membrane transport protein, MFSD2A, which is exclusively expressed in the endothelium of the blood–brain barrier.[81][82] Mechanism of action The 'essential' fatty acids were given their name when researchers found that they are essential to normal growth in young children and animals. The omega−3 fatty acid DHA, also known as docosahexaenoic acid, is found in high abundance in the human brain.[83] It is produced by a desaturation process, but humans lack the desaturase enzyme, which acts to insert double bonds at the ω6 and ω3 position.[83] Therefore, the ω6 and ω3 polyunsaturated fatty acids cannot be synthesized, are appropriately called essential fatty acids, and must be obtained from the diet.[83] References 1. ^ Jump up to:a b c d e f g h i "Omega-3 Fatty Acids". Office of Dietary Supplements, US National Institutes of Health. 26 March 2021. Retrieved 10 June 2021. 2. ^ Jump up to:a b c d e f "Essential Fatty Acids". Micronutrient Information Center, Linus Pauling Institute, Oregon State University. 1 May 2019. Retrieved 10 June 2021. 3. ^ "Essential Fatty Acids". Micronutrient Information Center, Oregon State University, Corvallis, OR. May 2014. Retrieved 24 May 2017. 4. ^ Scorletti E, Byrne CD (2013). "Omega-3 fatty acids, hepatic lipid metabolism, and nonalcoholic fatty liver disease". Annual Review of Nutrition. 33 (1): 231–48. doi:10.1146/annurev-nutr-071812-161230. PMID 23862644. 5. ^ Jacobsen, Charlotte; Nielsen, Nina Skall; Horn, Anna Frisenfeldt; Sørensen, Ann-Dorit Moltke (2013-07-31). Food Enrichment with Omega-3 Fatty Acids. Elsevier. p. 391. ISBN 978-0-85709-886-3. 6. ^ "Farmed fish: a major provider or a major consumer of omega-3 oils?| GLOBEFISH | Food and Agriculture Organization of the United Nations". www.fao.org. Retrieved 2022-02-04 EPA AND DHA EPA and DHA may affect many aspects of cardiovascular function including inflammation, peripheral artery disease, major coronary events, and anticoagulation. EPA and DHA have been linked to promising results in prevention, weight management, and cognitive function in those with very mild Alzheimer's disease. Health Benefits of DHA (Docosahexaenoic Acid) 

1. Reduces Heart Disease Risk 

2. May Improve ADHD(Attention deficit hyperactivity disorder ) 

3. Reduces the Risk of Early Preterm Births 

4. Fights Inflammation 

5. Supports Muscle Recovery After Exercise 

6. Helps Some Eye Conditions 

7. May Reduce Your Risk of Certain Cancers

8. May Help Prevent or Slow Alzheimer’s Disease 

9. Lowers Blood Pressure and Supports Circulation 

10. Aids Normal Brain and Eye Development in Babies 

11. Supports Men’s Reproductive Health 

12. May Help Protect Mental Health L GLUTATHIONE WHAT IS GLUTATHIONE Glutathione is a powerful antioxidant found in every cell in the body. It is made of three types of molecules known as amino acids. Amino acids combine in different patterns to make all of the proteins in the body. One unique thing about glutathione is that the body is able to make it in the liver, which is not true of most antioxidants. Glutathione has many important functions, including: • making DNA, the building blocks of proteins and cells • supporting immune function • forming sperm cells • breaking down some free radicals • helping certain enzymes function • regenerating vitamins C and E • transporting mercury out of the brain • helping the liver and gallbladder deal with fats • assisting regular cell death (a process known as apoptosis) Glutathione (GSH, /ˌɡluːtəˈθaɪoʊn/) is an antioxidant in plants, animals, fungi, and some bacteria and archaea. Glutathione is capable of preventing damage to important cellular components caused by reactive oxygen species such as free radicals, peroxides, lipid peroxides, and heavy metals.[2] It is a tripeptide with a gamma peptide linkage between the carboxyl group of the glutamate side chain and cysteine. The carboxyl group of the cysteine residue is attached by normal peptide linkage to glycine. What are benefits of glutathione? 

1. Antioxidant activity 

2. Preventing cancer progression 

3. Reducing cell damage in liver disease

4. Improving insulin sensitivity 

5. Reducing symptoms of Parkinson’s disease 

6. Reducing ulcerative colitis damage 

7. Treating autism spectrum disorders GINSEG EXTRACT What Is Ginseng? Ginseng is a plant. Different varieties of ginseng root have been used as treatments in Asia and North America for centuries. Ginseng is one of the most popular herbal medicines in the world. Ginseng has traditionally been used for a number of medical conditions. However, its benefits for most of them haven't been seriously researched. These include: • Build immunity. Some studies have found that ginseng may boost your immune system. There’s some evidence that one particular type of American ginseng extract might decrease the number and severity of colds in adults. • • Regulate blood sugar. Several studies in people have also shown that ginseng may lower blood sugar levels. • Improve focus. There’s some early evidence that ginseng might give a small, short-term boost to concentration and learning. Some studies of mental performance have combined ginseng with extract from leaves of the ginkgo tree, another traditional remedy said to help with dementia. While these studies are intriguing, many experts feel we need more evidence. 7 Proven Health Benefits of Ginseng 

1. Contains antioxidants that may reduce inflammation 

2. May benefit brain function 

3. Could improve erectile dysfunction 

4. May boost the immune system 

5. May have potential benefits against cancer 

6. May fight tiredness and increase energy levels 

7. Could lower blood sugar WHAT IS GINKGO BILOBA Ginkgo biloba is an herb used to treat altitude sickness (prevention), cerebral vascular insufficiency, cognitive disorders, dementia, dizziness/vertigo, intermittent claudication, macular degeneration/glaucoma, memory loss, premenstrual syndrome, SSRI-induced sexual dysfunction, and as a vasodilator 12 Benefits of Ginkgo Biloba 

1. Contains Powerful Antioxidants 

2. Can Help Fight Inflammation 

3. Improves Circulation and Heart Health 

4. Reduces Symptoms of Psychiatric Disorders and Dementia 

5. Improves Brain Function and Well-Being 

6. Can Reduce Anxiety 

7. Can Treat Depression 

8. Can Support Vision and Eye Health

9. Can Treat Headaches and Migraines 

10. Can Improve Asthma and COPD Symptoms 

11. Reduces PMS Symptoms 

12. Treats Sexual Dysfunction